Description
Cyclodextrins (CDs) are cyclic oligosaccharides formed by α-1,4 glycosidic bonds, typically consisting of 6, 7, or 8 D-glucopyranose units, known as α-, β-, and γ-cyclodextrins, respectively. CDs feature a truncated cone-shaped cylindrical structure with a hydrophobic inner cavity, a hydrophilic outer surface, and localized chiral environments. Their cavities can encapsulate various organic and inorganic small molecules to form inclusion complexes, enhancing the stability and solubility of active ingredients.
o-Cymen-5-ol (Isopropyl Methylphenol, abbreviated as IPMP) is a safe, effective, and stable antimicrobial preservative. It has been approved by the FDA for direct or indirect applications in food-related uses. With a long history of use as an antimicrobial agent, IPMP effectively inhibits the proliferation of Cutibacterium acnes, helping prevent the formation of acne.
Capryloyl Glycine (C₁₀H₁₉NO₃) is a white to off-white crystalline powder with a slight bitter taste and is primarily soluble in lipids while being almost insoluble in water. It is derived through the acylation of glycine, an amino acid that plays an essential role as a structural component of dermal proteins. Capryloyl Glycine helps regulate skin acidity, maintain skin balance, prevent excessive keratinization, inhibit harmful microorganisms, and control excessive sebum secretion, making it beneficial for acne-prone skin and seborrheic dermatitis management.
